BIOINFORMATICS

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BIOINFORMATICS

Target audience Faculties: (Medicine- dentistry- pharmacy- veterinary-science- agriculture- Biotechnology-Nursing) Undergrads - Postgrads -University staff – researchers

No Rating

(0 Reviews)

19 User Enrolled

What you will learn

1- What is bioinformatics? - Central Dogma - Principles of protein structure

2- Bioinformatics databases - Introduction - Nucleotide sequence databases - Protein sequence databases - Protein...

3- Alignment - Similarity and Homology - Similarity and Identity - Pairwise alignment algorithms. - Scoring Metrices...

4- Local Alignment - Unique Requirements of Database Searching -Heuristic Database Searching -BLAST...

5- Alignment continue - Multiple alignment - Structure alignment - Searching 3D Databases. - Classifying 3D shapes

6- Practical - How to read a phymology tree

Course Content

12 sections • 24 lectures • 18h 13m total length

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Requirements

From Zero to Hero

Description

Learning objectives:

Discuss the basic aspects of Bioinformatics and its significance in biological data analysis.
Discuss the different application areas of bioinformatic
Define Central Dogma (from gene to protein)
Classify different types of Biological Databases.
Importance of similarity search and Heuristic method.
Find high-scoring un-gapped segments among related sequences.
How to run a BLAST and interpreting program output.
Understanding the concept of E-values.
Asking biological questions with BLAST.
Knowing the difference between FASTA and BLAST.
Discuss multiple alignment and structure alignment
Discovery of 3D databases
Discuss evolution, taxonomy, phylogeny
How to differentiate between orthologs and paralogs